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Synthesized from the 5-carbon precursors isopentenyl diphosphate and dimethylallyl diphosphate; includes the carotenoids, which are precursors of vitamin A and also possess antioxidant effects.
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Macupatide acetate is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist designed for the research of type 2 diabetes. It works by improving insulin secretion responses and enhancing insulin sensitivity. In comparative studies, Macupatide acetate demonstrated a greater improvement in insulin sensitivity than Dulaglutide, even with similar weight reduction, and combining these agents showed additive effects.
Acts as a GIP receptor agonist.
Improves insulin secretion responses.
Enhances insulin sensitivity.
Potential for research in type 2 diabetes.
Shows superior insulin sensitivity improvement compared to Dulaglutide.
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Orbofiban acetate is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation. It is supplied for research use only and is not for human or clinical use.
Potent platelet GPIIb/IIIa antagonist that inhibits platelet aggregation.
Purity 98.13%.
Molecular formula C19H27N5O6 and molecular weight 421.45 g/mol.
Available as 25 mg vials for small-scale studies.
Soluble in DMSO: 150 mg/mL (sonication and warming to 60°C may be required; use newly opened DMSO).
Intended for in vitro and in vivo research; not for human use.
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PRT062607 (acetate) is a laboratory chemical intended for research use by experienced personnel. It is stable under recommended storage conditions and is not classified as a hazardous substance or mixture.
Not a hazardous substance or mixture.
Stable under recommended storage conditions.
Suitable for laboratory use.
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Macimorelin (EP-1572) acetate is an orally active GHSR agonist and a GH secretagogue that stimulates GH release. It is utilized in research for adult growth hormone deficiency (AGHD) and Cancer anorexia-cachexia syndrome (CACS).
Orally active GHSR agonist
Stimulates GH release
Used in adult growth hormone deficiency (AGHD) research
Used in cancer anorexia-cachexia syndrome (CACS) research
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(rel)-β-Tocopherol is a relative configuration of β-Tocopherol. β-Tocopherol is a lipid-soluble form of vitamin E that exhibits antioxidant activity. It is intended for research use only and not for human consumption.
β-Tocopherol (50 μM, 48 hours) has been observed to slightly inhibit the proliferation of A7r5 cells (10% inhibition) and CHO cells (20% inhibition), while showing no inhibitory effect on HeLa cells.
It also inhibits PMA-induced adhesion of human erythroleukemia (HEL) cells (11% inhibition) and the expression of integrins α4 and α5 on the cell surface when applied at 50 μM for 24 hours.
Appearance: Solid-Liquid Mixture
Color: Colorless to off-white
In ethanol: 50 mg/mL (119.99 mM); requires sonication.
In a solution of 10% Ethanol, 40% PEG300, 5% Tween-80, and 45% Saline: ≥ 1.25 mg/mL (3.00 mM) as a clear solution.
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An acetate form of (±)-α-tocopherol; inhibits heat-stress-induced decreases in blastocyst number in pregnant mice and GSH levels in isolated mouse zygotes in a model of hypothermia-induced pre-implantation embryonic death at 1 g/kg; prevents sidestream cigarette smoke-induced decreases in body weight and lung dynamic compliance and increases in lung resistance in mice at 1,050 IU/kg in the diet; increases IL-1β, IL-4, and IFN-γ levels in BALF in the same model
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(rel)-ML-SI3 is an active ingredient of ML-SI3, targeting three isoforms of TRPML. It functions as an inhibitor of TRPML1 and TRPML3, and a potent activator of TRPML2. This compound is supplied as a 10 mM solution in DMSO, ready for research applications.
Targets three isoforms of TRPML
Inhibitor of TRPML1 (IC50 = 3.1 μM) and TRPML3 (IC50 = 28.5 μM)
Potent activator of TRPML2 (EC50 = 3.3 μM)
Supplied as a 10 mM solution in DMSO
For research use only
Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light
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Alphadolone acetate is a steroid-class research compound described as having anesthetic and antinociceptive activity. It is supplied as a solid white to off-white powder for biochemical and pharmacological research; follow appropriate handling and storage guidelines.
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Smilagenin acetate is a sapogenin derivative extracted from patent US20030004147A1. It increases the expression of acetylcholine m2 receptors and can be used for the research of dementia. In vitro, Smilagenin acetate increases the expression of m2 receptors on CHO cells transfected with DNA for the m2 receptor.
Sapogenin derivative
Increases expression of acetylcholine m2 receptors
Can be used for the research of dementia
Effective in vitro on CHO cells transfected with m2 receptor DNA
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